> Advanced Technologies > Cyclic Peptides and Branched Peptides >

Advanced Technologies

Email : peptide@synpeptide.com

Tel : 86-21-50835580

Tel : 86-25-58861700

Request Consultation

Cyclic Peptides and Branched Peptides

Constraints by cyclization at either the backbone or side chain of the peptide are expected to reinforce and enhance the stability of the 3D-structure, such as α-helix, as well as the increment of the resistance to the enzymatic digestion.

Cyclized Peptides
Head-to-tail cyclization

X = NH : polypeptide
X = O : depsipeptide
(including N-methyl amino acids)
R=H : cyclo(X-Pro)
R=OH : cyclo(X-Hyp)
Staple peptide
site-specific ligation using olefin metathesis
Cyclization at side chain
X=O : lactone
X=S : thiolactone

[Asu 1,6]-Oxytocin
Branched Peptides(Isopeptides)
Branched at Asp/Glu
n=1 : Asp
n=2 : Glu
Branched at Lys
Branched at Ser/Thr

X=H : Ser
X=CH3 : Thr
We have lots of successful syntheses of the cyclic peptides as well as the branched peptides.
Please contact us for additional information or send an email to peptide@synpeptide.com 
To contact us by phone, please call 0086-21-50835580

Click here to leave a message